The goal of this living map of evidence is to act as a resource, attesting to the abundance and nature of the published peer-reviewed evidence being synthesized on natural health products for the treatment of COVID in the form of research reports that have used a systematic (and reproducible) strategy.

Statistical Overview – as of April 2023

Number of systematic reviews investigating the use of natural health products for the treatment of COVID: 168

Number of studies included in those reports: 3,494*

Number of participants included: 1,050,414*

*Note: numbers were not included in a number of the papers.








Research papers from 24 countries.
Most common ones:

China – 49 (32.7%)
India – 18 (12.0%)
Brazil – 12 (8.0%)
Iran – 12 (8.0%)
Italy – 7 (4.7%)







Most common NHPs include:

Patent herbal formulas: 51 (19.3%)
Vitamin D: 34 (12.9%)
Vitamin C: 25 (9.5%)
Zinc: 12 (4.5%)
Probiotics: 11 (4.2%)
Ayurveda: 9 (3.4%)
Flavonoids: 9 (3.4%)
Turmeric: 9 (3.4%)

Search terms: systematic review, COVID, COVID-19, SARS-CoV-2, “Severe acute respiratory syndrome coronavirus 2″, “viral respiratory tract infections”, “naturopathic treatment”, “Traditional Chinese medicine”, nutraceutical, “natural product” botanical, herb, “herbal medicine”, “medicinal herbs”, “medicinal plants”, vitamin, mineral